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Membrane Cassettes

Your Professional Membrane Cassettes Supplier

Hangzhou Guidling Technology CO.,LTD is an innovative manufacturer focusing on providing solutions (clarification, separation and concentration, etc.) in the downstream field of biopharmaceutical. Guidling Technology has successfully developed centrifugal filter devices, ultrafiltration & microfiltration cassettes and TFF device and system, depth filter modules, virus clearance filter, etc.

Why Choose Us

ISO-Certified Quality Management

We are certified under ISO 9001:2015 / GB/T 19001-2016 by internationally recognized bodies (IAF/IAS), ensuring strict process control and consistently reliable product quality throughout manufacturing.

Scalable Filtration Solutions

We provide integrated clarification, filtration, and concentration systems designed to support seamless scale-up from laboratory to full-scale industrial production.

Proven Biopharma Applications

Our filtration technologies are widely used in antibody, vaccine, and biologics manufacturing, enabling stable and efficient clarification, separation, and virus removal processes.

Parameter

Maximum Inlet Pressure	≤4.2bar(60.9 psi)
Forward Transmembrane Pressure	5.5 bar (80 psi) at 4-45 °C,220 hours continuous(3 hours continuous,0.1m2 format only) 2.5 bar (40 psi) at 4-50 °C, 50 hours continuous
Reverse Transmembrane Pressure	30 psi (2.1 bar) at 25 °C,3 min intervals, 10 cycles(5 cycles, micro format only)
Maximum Caustic Exposure	1.0 N NaOH at 50 °C(Contact us for exposure parameters.)
PH Range	1-14

Benefits of Membrane Cassettes

High Filtration Efficiency

Provides stable permeate quality with high flux and effective removal of suspended solids and macromolecules.

Modular And Scalable Design

Easy to expand or integrate into different system capacities and process requirements.

Easy Cleaning And Strong Chemical Resistance

Compatible with CIP cleaning , ensuring long service life and reduced downtime.

Membrane Cassettes Cleaning and Storage Procedure

For ultrafiltration and microfiltration cassettes, after washing with water, wash with 0.5M NaOH for 30 minutes, and then enter the lye with the diaphragm valve fully open. After the reflux pH rises, the return pipe is put back into the lye cup. The diaphragm valve rotates so that the reflux pressure gauge reach about 0.2bar. The three tubes were washed in a container for 30 minutes; then they were preserved with 0.1M NaOH. After cleaning the 1kd and 3kd ultrafiltration membrane with lye, it must be washed with water to neutral and then stored in 1.5% sodium bisulfite.

Application of Membrane Cassettes

Food: Contributes to improved productivity in separation and filtration processes in the food industry through both software and hardware approaches.

Pharmaceuticals: Achieves increased yield and productivity of target substances (antibodies, proteins, vaccines, enzymes, etc.)

Certificate

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Flexible Global Shipping Solutions

We support multiple shipping methods including sea freight, air freight, rail transportation, and express delivery to meet different delivery timelines and project requirements. Professional packaging and export handling ensure safe and efficient transportation for international orders.

FAQ

Q: How to choose the membrane pore size?

A: For ultrafiltration concentration: you can choose a membrane pore size that is 3-5 times smaller than the target protein. For example, if the target protein is 150kd, you can choose a 30kd or 50kd membrane cassette. For clarification and filtration: supernatant after crushing yeast, CHO cell culture medium, etc., generally choose 0.22 or 0.45μm membrane cassette.

Q: How to choose the membrane area?

A: According to the sample processing volume and the customer’s expected processing time to choose appropriate membrane area. Generally, the recommended treatment volume of 0.11m2 membrane cassette is 0.5-4L, the recommended treatment volume of 0.5m2 membrane cassette is 4-20L, and the recommended treatment volume of 1.3m2 membrane cassette is 20-100L. For example, the sample volume of the customer is 150L, and the molecular weight of the target protein is 30kd. It is expected to complete the concentration of 150L sample to 10L within 2 hours. The LMH obtained by using a 5kd membrane cassette in a small amount of testing is 20. The membrane area can be calculated according to the treatment capacity and LMH. 140L/20LMH/2h=3.5m2.

Q: What is the lifespan and usage times of the ultrafiltration membrane cassette?

A: The service life of the membrane bag is very long. Under the premise of normal use and maintenance, the lifespan and usage times of membrane cassette can be longer than the packing. Complete regeneration, avoid contact with some unknown high-concentration organic reagents and keep them reasonably.

As one of the leading membrane cassettes manufacturers and suppliers in China, we also support customized service. We warmly welcome you to wholesale high quality membrane cassettes in stock here from our factory. For quotation, contact us now.

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